Ensuring Transparency in Medical Research with the GAMER Statement

As generative artificial intelligence (GAI) tools become increasingly integrated into medical research, clear and transparent reporting of their use is essential to maintain scientific integrity. The GAMER Statement, short for Guideline for the Appropriate use of Generative Artificial Intelligence in MEdical Research Reporting, provides researchers with a structured framework to disclose AI involvement throughout the research lifecycle.

The GAMER Statement outlines 9 key reporting items designed to promote transparency and reproducibility when generative AI tools like ChatGPT, Bard, or others assist with tasks ranging from drafting manuscripts to supporting data analysis. Researchers are encouraged to explicitly name the AI tools used, specify model versions, describe prompt techniques, and clearly detail the roles AI played throughout the research and writing process including study design, data handling, and manuscript development. Importantly, authors must also explain how AI-generated content was verified for accuracy and how data privacy was protected.

By following these guidelines, researchers can prevent issues such as ghostwriting, undisclosed AI assistance, and potential biases or inaccuracies introduced by AI tools. This transparency builds trust in published findings and supports robust peer review.

Embracing these standards ensures that the surge of AI-assisted research advances knowledge responsibly while maintaining the highest ethical and scientific standards.

To help medical researchers implement the GAMER Statement in their own work, a comprehensive checklist is available as a downloadable resource. This checklist guides authors step by step on how to report AI involvement thoroughly and ethically.

Completing this checklist ensures comprehensive and standardized reporting of generative AI use in your study. Please include the completed checklist with your journal submission to facilitate transparent evaluation and uphold research integrity.

References

1. Gómez, Víctor M., Zeraatkar, Diplomate R., Matthews, Kelly, et al. “Reporting Guideline for the Use of Generative Artificial Intelligence Tools in Medical Research: The GAMER Statement.” BMJ Evidence-Based Medicine, May 13, 2025. https://ebm.bmj.com/content/ebmed/early/2025/05/13/bmjebm-2025-113825.long.
2. Gómez, Víctor M., Zeraatkar, Diplomate R., Matthews, Kelly, et al. “Reporting Guideline for the Use of Generative Artificial Intelligence Tools in Medical Research: The GAMER Statement.” EQUATOR Network. Accessed October 14, 2025. https://www.equator-network.org/reporting-guidelines/reporting-guideline-for-the-use-of-generative-artificial-intelligence-tools-in-medical-research-the-gamer-statement/.